Key Features

• Provides up-to-date information on every aspect of newborn evaluation and management in a new, visually improved format featuring more than 500 all-new illustrations　integrated within each chapter.
• Includes　greatly expanded Neurology and Hematology sections　that highlight the knowledge and expertise of　new co-editor, Dr. Sandra E. Juul.

Table of Contents

Part I  Overview
1. Neonatal and Perinatal Epidemiology
2. Biomedical Informatics in Neonatology
3. Ethics, Data, and Policy in Newborn Intensive Care
4. Global Neonatal Health

Part II   Fetal Growth and Development
5. The Placenta
6. Abnormalities of Fetal Growth
7. Multiple Gestations and Assisted Reproductive Technology (ART)
8. Prematurity and Stillbirth
9. Nonimmune Hydrops

Part III   Maternal Health
10. Maternal Diabetes
11. Maternal Medical Disorders of Fetal Significance
12. Hypertensive Complications of Pregnancy
13. Prenatal Drug Exposure

Part IV   Labor and Delivery
14. Antepartum Fetal Assessment
15. Complicated Deliveries
16. Obstetric Analgesia and Anesthesia

Part V   Genetics
17. The Human Genome and Neonatal Care
18. Prenatal Diagnosis
19. The Dysmorphic Infant
20. Chromosome Disorders

Part VI   Metabolic Disorders of the Newborn
21. Introduction to Metabolic and Biochemical Genetic Diseases
22. Inborn Errors of Carbohydrate, Ammonia, Amino Acid, and Organic Acid Metabolism
23. Lysosomal Storage, Peroxisomal, and Glycosylation Disorders and Smith-Lemli-Opitz Syndrome Presenting in the Neonate

Part VII  Basic Newborn Care
24. Newborn Resuscitation
25. Newborn Evaluation
26. Newborn Nursery Care
27. Newborn Screening

Part VIII   High-Risk Newborn Care
28. Infant Transport
29. Temperature Regulation
30. Fluid, Electrolyte and Acid-Base Balance
31. Extremely Low-Birth-Weight Infants
32. Late Preterm Infants
33. Neonatal Pharmacology
34. Neonatal Pain and Stress
35. Palliative Care

Part IX   Immunology and Infections
36. Immunology of the Fetus and Newborn
37. Viral Infections of the Fetus and Newborn
38. Toxoplasmosis, Syphilis, Malaria, and Tuberculosis
39. Newborn Sepsis and Meningitis
40. Nosocomial Infections
41. Fungal Infections

Part X   Respiratory System
42. Lung Development
43. Control of Breathing
44. Neonatal Pulmonary Physiology
45. Neonatal Respiratory Therapy
46. Respiratory Disorders in the Preterm Infant
47. Respiratory Disorders in the Term Infant
48. Bronchopulmonary Dysplasia
49. Surgical Disorders of the Chest and Airways

Part XI   Cardiovascular System
50. Developmental Biology of the Heart
51. Cardiovascular Compromise in the Newborn
52. Persistent Pulmonary Hypertension
53. Fetal and Neonatal Echocardiography
54. Patent Ductus Arteriosus in the Preterm Infant
55. Congenital Heart Disease
56. Perinatal Arrhythmias
57. Long-Term Neurologic Outcomes in Children with Congenital Heart Disease

Part XII   Neurologic System
58. Central Nervous System Development
59. Congenital Malformations of the Central Nervous System
60. Brain Injury in the Preterm Infant
61. Brain Injury in the Term Infant
62. Neuroprotection Strategies for the Newborn
63. Neonatal Neuroimaging
64. Neonatal Neuromuscular Disorders
65. Neonatal Seizures
66. Risk Assessment and Neurodevelopmental Outcomes

Part XIII   Nutrition
67. Breastfeeding
68. Enteral Nutrition for the High-Risk Neonate
69. Parenteral Nutrition for the High-Risk Neonate

Part XIV   Gastrointestinal System
70. Gastrointestinal Tract Development
71. Structural Anomalies of the Gastrointestinal Tract
72. Innate and Mucosal Immunity in the Developing GI Tract
73. Abdominal Wall Defects
74. Neonatal Gastroesopheageal Reflux
75. The Intestinal Microbiome
76. Necrotizing Enterocolitis and Short Bowel Syndrome
77. Disorders of the Liver

Part XV   Hematologic System and Disorders of Bilirubin Metabolism
78. Developmental Hematology
79. Neonatal Thrombotic Disorders
80. Neonatal Platelet Disorders
81. Neonatal Erythrocyte Disorders
82. Neonatal Transfusion
83. Neonatal Leukocyte Disorders
84. Neonatal Indirect Hyperbilirubinemia AND KERNICTERUS

Part XVI  Neoplasia
85. Congenital Malignant Disorders

Part XVII   Renal and Genitourinary Systems
86. Renal Development
87. Developmental Abnormalities of the Kidneys
88. Developmental Abnormalities of the Genitourinary System
89. Clinical Evaluation of Renal and Urinary Tract Disease
90. Acute Kidney Injury and Chronic Kidney Disease
91. Glomerulonephropathies and Disorders of Tubular Function
92. Urinary Tract Infections
93. Neonatal Hypertension

Part XVIII   Endocrine Disorders
94. Developmental Endocrinology
95. Disorders of Calcium and Phosphorus Metabolism
96. Disorders of the Adrenal Gland
97. Disorders of Sexual Differentiation
98. Disorders of the Thyroid Gland
99. Disorders of Carbohydrate Metabolism

Part XIX   Craniofacial and Orthopedic Conditions
100. Craniofacial Malformations
101. Common Neonatal Orthopedic Conditions
102. Skeletal Dysplasias and Connective Tissue Disorders

Part XX   Dermatologic Conditions
103. Newborn Skin: Development and Basic Concepts
104. Congenital and Hereditary Disorders of the Skin
105. Infections of the Skin
106. Common Newborn Dermatoses
107. Cutaneous Congenital Defects