Principles of Pharmacology, 4/e

About

Principles of Pharmacology: the Pathophysiologic Basis of Drug Therapy, 4th Edition, offers an integrated mechanism-based and systems-based approach to contemporary pharmacology and drug development. An easy-to-follow format helps first- and second-year students grasp challenging concepts quickly and efficiently. Each chapter presents a clinical vignette illustrating a therapeutic problem within a physiologic or biochemical system; followed by a discussion of the biochemistry, physiology and pathophysiology of the system; and concluding with a presentation of the pharmacology of the drugs and drug classes that activate or inhibit the system by interacting with specific molecular and cellular targets.

Key Features               

• Comprehensive updates to all chapters, including recently approved drugs
• Nearly 40 popular and practical Drug Summary Tables with state-of-the-art information on clinical applications, serious and common adverse effects, contraindications, and therapeutic considerations
• A new chapter on drug transporters, and extensively revised information on drug-receptor interactions, pharmacodynamics, drug toxicity, and pharmacogenomics
• Key changes to Section 1: Fundamental Principles of Pharmacology, which now provides a comprehensive framework for material in all subsequent chapters. 
• Hundreds of meticulously updated illustrations, including many that are new or substantially modified to highlight new understanding of physiologic, pathophysiologic, and pharmacologic mechanisms.